Now that you have set up your User Preferences and have gone through the Properties Setup, I have a couple of suggestions that may make your Blender experience a little bit better.

Clean up the desktop a bit by moving the Camera and default Lamp to another collection. To move an object, select one by right-clicking (RMB), or multiples by holding Shift + RMB. With your arrow cursor still in the 3D window, select the M key to move, and choose the Collection you want to send them to, or create a new one.
If you haven't done so already, switch the render engine from Eevee to Cycles Render. You probably already made the switch if you went through the previous setups, but if not, look in the Render Properties.
Turn on Automatically Pack Into .blend (File > External Data > Automatically Pack Into .blend) ----- SEE IMAGE RIGHT ------
Make any other changes you'd like to be part of your Startup File.

You are now ready to save your Startup File that will keep all your settings that you configured as the default settings.

All you need to do is select File > Defaults > Save Startup File. You can also use the keyboard command, Ctrl + U. You will be prompted to confirm your selection.

If you ever change a setting that you want to be part of your Startup File, simple repeat the above step.